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为探讨胃肠外营养（ＴＰＮ）添加精氨酸（Ａｒｇ）对胃癌术后患者淋巴细胞免疫功能的影响及意义，对３６例胃癌术后患者进行了ＴＰＮ支持的前瞻性研究，检测常规ＴＰＮ和ＴＰＮ添加Ａｒｇ支持前后患者的Ｔ淋巴细胞亚群、ＮＫ细胞活性、ＩＬ２和ＣＤ２５水平变化。结果：常规ＴＰＮ支持前后患者的Ｔ淋巴细胞亚群、ＮＫ细胞活性、ＩＬ２和ＣＤ２５水平变化无明显差异，而ＴＰＮ添加Ａｒｇ支持后患者的ＣＤ４、ＣＤ４／ＣＤ８比值、ＮＫ细胞活性和ＩＬ２水平均明显增加（Ｐ＜０．０５）。本研究结果显示：常规ＴＰＮ不能纠正胃癌术后患者的淋巴细胞免疫功能抑制，但ＴＰＮ添加Ａｒｇ则可促进ＩＬ２生成增加，ＮＫ细胞活性增强，改善了胃癌术后患者的淋巴细胞免疫功能，提示ＴＰＮ添加Ａｒｇ有免疫促进作用
To investigate the effect and significance of adding arginine (Arg) to parenteral nutrition (TPN) on lymphocyte immune function in postoperative patients with gastric cancer, a prospective study of TPN support was performed on 36 patients with postoperative gastric cancer to detect conventional TPN and The T lymphocyte subsets, NK cell activity, IL 2 and CD25 levels of patients before and after TPN addition of Arg support. Results: There was no significant difference in T lymphocyte subsets, NK cell activity, IL-2 and CD25 levels between patients before and after conventional TPN support, and the ratios of CD4, CD4/CD8, NK cell activity, and IL in TNP-added Arg-supported patients. 2 The levels increased significantly (P<0.05). The results of this study show that: conventional TPN can not correct lymphocyte immune function inhibition in patients with gastric cancer after surgery, but TPN and Arg can promote the increase of IL 2 production, NK cell activity increased, improved lymphocyte immune function in patients with gastric cancer after surgery, Tip TPN add Arg has immune promoting effect