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脑内出血和静注苯丙胺或其有关复合制剂的关系日益得到认识,但较少注意口服或吸入这些药后可发生脑内出血。本文报告4例在口服或吸入苯丙胺后发生脑内出血。例1服用4～5片盐酸二乙胺苯丙酮(与苯丙胺有关的拟交感神经药)后,出现左手笨拙和精神错乱,左侧偏盲、偏瘫,血压198/100mmHg,CT扫描示右后顶2×3cm密度增高区,15天后发生左侧肢体的局限性癫痫,脑血管造影示右大脑中动脉区血管不规则及若干小血管闭塞。例2口服硫酸甲基苯丙胺1～20片/周,数月后右侧偏瘫、偏盲,CT示左侧丘脑出血,3年后再次发生左侧偏瘫,CT示右壳核新
The relationship between intracerebral hemorrhage and intravenous amphetamines or their combination regimens is increasingly recognized, but less attention has been given to the intracerebral hemorrhage that can occur after oral or inhalation of these drugs. This article reports four patients who developed intracerebral hemorrhage after oral or inhaled amphetamine. Example 1 After taking 4 to 5 tablets of amphetamines (amphetamine-related sympathomimetic drugs), left hand clumsiness and delirium, left hemianopia, hemiplegia, blood pressure 198 / 100mmHg, and CT scan showed right back top 2 × 3cm increased density of the area, 15 days after the occurrence of the limitations of the left limb epilepsy, cerebral angiography showed right middle cerebral artery vascular irregularities and a number of small vessel occlusion. Example 2 oral methamphetamine 1 to 20 tablets / week, a few months after the right hemiplegia, hemianopia, CT showed left thalamic hemorrhage, 3 years after the recurrence of the left hemiplegia, CT showed the right new putamen