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目的调查广西艾滋病(HIV/AIDS)合并结核病(TB)双重感染情况,并分析其影响因素。方法收集2013年广西某传染病医院就诊的1 086例艾滋病患者的临床资料,分析其HIV/TB双重感染情况,运用二分类Logistic回归模型进行TB/HIV双重感染影响因素分析。结果 1 086例艾滋病患者中,HIV/TB双重感染527例(48.53%)。其中单纯肺结核245例(46.49%),肺结核合并肺外结核197例(37.38%),单纯肺外结核85例(16.13%)。多因素Logistic回归分析显示,男性患者(OR=1.472,95%CI=1.056~2.054)、>50岁者(OR=1.477,95%CI=1.111~1.964)、CD4+T淋巴细胞计数低者(OR=1.347,95%CI=1.022~1.776)及血小板计数较高者(OR=2.079,95%CI=1.360~3.179)更易感染TB。结论广西HIV/AIDS患者TB的感染率较高,性别、年龄、血小板和CD4+T淋巴细胞计数是其感染TB的危险因素,应根据患者的不同临床特征制定相应的防治措施。
Objective To investigate the double infection of HIV / AIDS and tuberculosis (TB) in Guangxi and to analyze its influential factors. Methods The clinical data of 1086 AIDS patients admitted to an infectious disease hospital in Guangxi in 2013 were collected to analyze their HIV / TB double infection status. The binary logistic regression model was used to analyze the influencing factors of TB / HIV dual infection. Results Among 1 086 AIDS patients, 527 were HIV / TB double infections (48.53%). Among them, 245 cases were simple tuberculosis (46.49%), 197 cases were tuberculosis combined with extrapulmonary tuberculosis (37.38%) and 85 cases were simple extrapulmonary tuberculosis (16.13%). Multivariate logistic regression analysis showed that the percentage of CD4 + T lymphocyte count (OR = 1.472, 95% CI = 1.056 ~ 2.054), age> 50 years OR = 1.347, 95% CI = 1.022 ~ 1.776) and higher platelet count (OR = 2.079,95% CI = 1.360 ~ 3.179). Conclusion The prevalence of TB infection in HIV / AIDS patients in Guangxi is high. Sex, age, platelet count and CD4 + T lymphocyte count are the risk factors of TB infection in Guangxi. Corresponding control measures should be formulated according to different clinical characteristics of patients.