论文部分内容阅读
应用流式细胞术观察７５ｍＧｙＸ射线诱导小鼠胸腺细胞凋亡及细胞周期进程的适应性反应。结果表明，１．５或２．０Ｇｙ全身照射后，小鼠胸腺细胞凋亡小体（ＴＡＢ）百分数明显增加，Ｓ期ＴＡＢ百分数明显减少，而Ｇ０／Ｇ１和Ｇ２＋Ｍ期ＴＡＢ百分数明显增加；当１．５或２．０Ｇｙ（攻击剂量，Ｄ２）照射前６ｈ给予７５ｍＧｙ（诱导剂量，Ｄ１）照射时，明显减轻Ｄ２对胸腺细胞凋亡及细胞周期进程的损伤作用。提示，低剂量辐射可诱导胸腺细胞凋亡及细胞周期进程的适应性反应。
Flow cytometry was used to observe the adaptive response of 75mGy X - ray induced thymocyte apoptosis and cell cycle progression in mice. The results showed that after 1.5 or 2.0Gy whole body irradiation, the percentage of apoptotic bodies (TAB) in mouse thymocytes was significantly increased, the percentage of TAB in S phase was significantly decreased, while the percentage of TAB in G0 / G1 and G2 + M phases was significantly increased. .5 or 2.0Gy (challenge dose, D2) irradiation 6h 6h given 75mGy (induction dose, D1) irradiation, significantly reduce the effects of D2 on thymocyte apoptosis and cell cycle progression. Tip, low dose radiation can induce thymus apoptosis and cell cycle progression of the adaptive response.