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目的探讨妊娠早期人体胎盘中多巴胺－β－羟化酶（ＤＢＨ）活性及其与早期妊娠的关系。②方法应用分光光度法对妊娠６～９周人体胎盘绒毛中ＤＢＨ活性进行了测定。③结果妊娠第８周胎盘绒毛中ＤＢＨ的活性明显高于第６，７周，差异有显著性（Ｆ＝５．７６，ｑ＝５．８８，３．６４，Ｐ＜０．０５，０．０１），其他各组间比较差异无显著性（ｑ＝０．０６～３．２４，Ｐ＞０．０５）。④结论妊娠早期人体胎盘中已存在着ＤＢＨ，并可能参与妊娠的维持。
Objective To investigate the activity of dopamine-β-hydroxylase (DBH) in human placenta during early pregnancy and its relationship with early pregnancy. Methods The spectrophotometric method was used to determine the activity of DBH in human placenta from 6 to 9 weeks of gestation. Results The activity of DBH in placenta villus at the 8th week of pregnancy was significantly higher than that of the 6th and 7th week (F = 5.76, q = 5.88, 3.64, P <0.05,0. 01). There was no significant difference among the other groups (q = 0.06 ~ 3.24, P> 0.05). ④ Conclusion DBH is already present in human placenta in early pregnancy and may be involved in the maintenance of pregnancy.