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目的:了解贵州省12~15岁青少年恒牙龋病状况，为开展青少年口腔预防保健提供科学依据。方法:采用多阶段分层等容量随机抽样的方法，抽取贵州省城乡12~15岁青少年共3 771人。使用CPI探针检查全口牙冠龋病情况，计算不同特征人群患龋率、龋补填充比、窝沟封闭率等。结果:贵州省12~15岁青少年恒牙患龋率为29.62%（1 117/3 771），龋补充填比2.53，窝沟封闭率2.17%。城市青少年恒牙患龋率31.43%，高于农村青少年的27.77%，差异有统计学意义（n χn 2=6.071，n P<0.01）；女性恒牙患龋率33.16%，高于男性的26.10%，差异有统计学意义（n χn 2=22.526，n P<0.01）。n 结论:贵州省12~15岁人群患龋率城市高于农村，女性高于男性；且龋补充填比及窝沟封闭率均较低。贵州省青少年的恒牙患龋情况严峻，应提高口腔公共卫生预防管理能力，有效控制青少年口腔疾病的发生。“,”Objective:To understand the situation of permanent teeth caries in adolescents aged 12-15 years in Guizhou, so as to provide scientific evidences for the prevention of teeth caries in adolescents.Methods:A total of 3 771 adolescents aged 12-15 in urban and rural areas of Guizhou were selected by multi-stage stratified random sampling with equal capacity. CPI probe was used to detect crown caries. The rate of permanent teeth caries, the rate of caries filling and the rate of pit and fissure sealant were calculated among different groups.Results:Among the adolescents aged 12-15 in Guizhou, the rate of permanent teeth caries, the rate of caries filling and the rate of pit and fissure sealant were 29.62% (1 117/3 771) , 2.53 and 2.17%, respectively. The caries rate of permanent teeth among adolescents in urban was 31.43%, which was higher than that in rural areas (27.77%) with statistically significant difference (n χ2=6.071, n P<0.01) . The caries rate of permanent teeth in women was 33.16%, which was higher than that of 26.10% in men with statistically significant difference (n χ2=22.526, n P<0.01) .n Conclusions:The incidence rates of caries among adolescents aged 12-15 in Guizhou are higher in urban and females than those in rural areas and males. Compared with the national level, the filling rate of dental caries and the closure rate of pits and furrows are low. The situation of permanent teeth caries among adolescents in Guizhou is serious, and it is necessary to improve the ability of oral public health prevention and management, so as to effectively control the occurrence of oral caries among adolescents.