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总结分析了１４例腭部中线恶性网织细胞增生症（中线恶网）的临床病理及免疫组化特点。１４例（男１０例，女４例）患者发病高峰年龄在２１～３０岁年龄段，临床表现为腰部肿胀、渍疡或穿孔，可合并鼻腔、上颌窦及皮肤损害。光镜下以凝固性坏死、非特异性炎症背景上散布异型淋巴样细胞为特征，其中２例标本在部分高倍视野中出现异型淋巴样细胞似恶性淋巴瘤的增生改变。免疫组化结果显示：１４例中１０例之异型淋巴样细胞来源于Ｔ淋巴细胞，另４例可能由于抗体丢失等原因无法确立来源。作者认为中线恶网本质为恶性淋巴瘤，且大部分为Ｔ细胞源性。但其在临床及组织学上与恶性淋巴瘤有一定差别，应作为一个独立概念存在。此外，中线恶网在形态学上可以向恶性淋巴瘤转化。
The clinicopathological and immunohistochemical features of 14 cases of palatal midline malignant reticulosis (nemesis) were summarized and analyzed. Fourteen patients (10 males and 4 females) developed a peak age of 21-30 years old. Their clinical manifestations were swollen lumbar, ulceration or perforation of the lumbar spine. They could be combined with nasal cavity, maxillary sinus and skin lesions. Light microscopy coagulation necrosis, non-specific inflammatory background scattered atypical lymphoid cells characterized by 2 cases of specimens in some high power field appear atypical lymphoid cells like malignant lymphoma hyperplasia. Immunohistochemical results showed that 10 cases of allogeneic lymphoid cells originated from T lymphocytes in 14 cases and the other 4 cases could not be established due to the loss of antibodies. The author believes that the essence of the nemesis is malignant lymphoma, and most of them are T-cell-derived. However, its clinical and histological malignant lymphoma are some differences, should exist as an independent concept. In addition, the nemesis is morphologically morphologically malignant lymphomas.