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目的:通过Meta分析明确慢性心力衰竭患者再入院的相关风险因素。方法:计算机检索PubMed、Cochrane Library、Web of Science、Embase、SinoMed、CNKI、万方数据库和维普数据库,检索时限为建库至2019年12月31日。采用RevMan 5.3软件进行Meta分析。结果:共纳入19篇文献,纳入患者185 545例,包括34项相关风险因素。有统计学意义的风险因素包括抑郁情绪(n OR=3.87,95%n CI:2.87~5.23,n P<0.01)、独居(n OR=1.12,95%n CI:1.01~1.24,n P=0.03)、合并高血脂或糖尿病(n OR=1.16,95%n CI:1.14~1.19,n P<0.01)、高盐饮食(n OR=3.36,95%n CI:2.60~4.35,n P<0.01)、肾功能下降(n OR=2.00,95%n CI:1.95~2.04,n P<0.01)、射血分数下降性心力衰竭(n OR=2.71,95%n CI:1.93~3.73,n P<0.01)、贫血(n OR=1.43,95%n CI:1.27~1.60,n P<0.01)、感染(n OR=1.12,95%n CI:1.00~1.25,n P=0.04)。n 结论:抑郁情绪、独居、合并高血脂或糖尿病、高盐饮食、肾功能下降、射血分数下降性心力衰竭、贫血、感染是慢性心力衰竭患者再入院的相关风险因素。“,”Objective:To explore the relevant risk factors for readmission of patients with chronic heart failure by Meta-analysis.Methods:We searched the PubMed, Cochrane Library, Web of Science, Embase, SinoMed, China National Knowledge Infrastructure (CNKI) , Wanfang Data and VIP Database by computer, and the search time limit was from the establishment of the database to December 31, 2019. RevMan 5.3 software was used for Meta-analysis.Results:A total of 19 articles were included, including 185 545 patients and 34 related risk factors.Statistically significant risk factors included depression [n OR=3.87, 95%n CI (2.87-5.23) , n P<0.01], living alone [n OR=1.12, 95%n CI (1.01-1.24) , n P=0.03], combined with hyperlipidemia and diabetes [n OR=1.16, 95%n CI (1.14-1.19) , n P<0.01], high-salt diet [n OR=3.36, 95%n CI (2.60-4.35) , n P<0.01], decreased renal function [n OR=2.00, 95%n CI (1.95-2.04) , n P<0.01], heart failure with reduced ejection fraction [n OR=2.71, 95%n CI (1.93-3.73) , n P<0.01], anemia [n OR=1.43, 95%n CI (1.27-1.60) , n P<0.01]and infection [n OR=1.12, 95%n CI (1.00-1.25) , n P=0.04].n Conclusions:Depression, living alone, combined with hyperlipidemia and diabetes, high-salt diet, decreased renal function, heart failure with reduced ejection fraction, anemia and infection are related risk factors for readmission in patients with chronic heart failure.