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介绍了抗癫痫药物苯妥英钠(DPH)血液浓度监测和临床体会,探讨DPH单药的临床应用价值。对单药DPH组、双药组、三种以上药物组进行了血液浓度监测,结果显示首次三组有效率无明显差异(F>0.05).经调整DPH血液浓度后3组比较,其有效率有显著杜差异(P<0.05)。双药组与三种以上组有效率无显著性差异(P>0.05).表明控制癫痫大发作与部分性发作单药较双药和三种以上药物级效果为佳。
The anti-epileptic drug phenytoin sodium (DPH) blood concentration monitoring and clinical experience were introduced to explore the clinical value of single drug DPH. Blood concentration monitoring of single drug DPH group, double drug group and three or more drug groups showed no significant difference (F> 0.05) for the first three groups. The DPH blood concentration after adjustment in the three groups, the effective rate was significantly Du difference (P <0.05). Two-drug group and more than three groups no significant difference in the efficiency (P> 0.05). Show that the control of epileptic seizures and partial seizures of single drug more than two drugs and three kinds of drug-level effect is better.