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本文采用队列和队列内病例对照研究的方法,探讨了广西锡矿工人接尘和鼻咽癌高发的关系,队列对象7818人,其中,鼻咽癌患者28例,按年龄、性别配对照113例,用SAS软件进行单因素分析和多因素非条件Logistic回归分析。结果接尘组鼻咽癌发病的相对危险度为1.41,P>0.05;病例组与对照组比较OR=0.88,P>0.05;累积接尘量与鼻咽癌发生也未见相关(X2=1.33,P>0.05)。表明:无论是队列资料还是病例对照资料,均不支持职业接尘与鼻咽癌发病有关。但非职业因素中提示:食咸鱼习惯和出生地可能与鼻咽癌发病有关,吸烟、饮酒、婚姻和文化程度等与鼻咽癌发生无关。
In this paper, the cohort and cohort case-control study methods to explore the tin miners in Guangxi and the high incidence of nasopharyngeal dust, the cohort of 7818 patients, of which 28 cases of nasopharyngeal carcinoma, according to age and sex matched control 113 cases , Using SAS software univariate analysis and multivariate non-conditional Logistic regression analysis. Results The relative risk of nasopharyngeal carcinoma in dust-exposed group was 1.41, P> 0.05; OR = 0.88, P> 0.05 in case group and control group; Nor related (X2 = 1.33, P> 0.05). That: no matter the cohort data or case control data, do not support occupational dust and nasopharyngeal cancer incidence. However, non-occupational factors suggest: eating salted fish habit and place of birth may be related to the incidence of nasopharyngeal carcinoma, smoking, drinking, marriage and education has nothing to do with the occurrence of nasopharyngeal carcinoma.