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目的观察中西医结合治疗难治性肾病综合征的临床疗效。方法将60例患者随机分为两组,对照组30例给予激素、环磷酰胺治疗;治疗组30例,在对照组治疗基础上配合中药治疗。观察两组临床疗效、副作用发生率等。结果总有效率治疗组为96.67%,对照组为70%,两组比较差异有显著性意义(P<0.05);两组在继发感染、柯兴样体征、白细胞减少、肝功能异常、胃肠道反应等方面比较,差异均有显著性或非常显著性意义(P<0.05,P<0.01)。结论中西医结合治疗难治性肾病综合征疗效明显优于纯西医治疗,且副作用少,值得推广应用。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of refractory nephrotic syndrome. Methods Sixty patients were randomly divided into two groups. The control group was treated with hormones and cyclophosphamide. Thirty patients in the treatment group were treated with the traditional Chinese medicine on the basis of the control group. The clinical efficacy and the incidence of side effects were observed. Results The total effective rate was 96.67% in the treatment group and 70% in the control group, with significant difference between the two groups (P <0.05). There were no significant differences in secondary infection, Cushing’s syndrome, leukopenia, abnormal liver function, Intestinal response and other aspects, the differences were significant or very significant (P <0.05, P <0.01). Conclusion Integrative treatment of refractory nephrotic syndrome was significantly better than pure Western medicine treatment, and fewer side effects, it is worth promoting the application.