Effects of endothelin-1 on hepatic stellate cell proliferation, collagen synthesis and secretion, in

• 作 者: Chuan-YongGuo Jian-YeWu Yun-Bi
• 机 构: DepartmentofGastroenterology,DepartmentofGastroenterology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2004年18期
• 关键词: 内皮素-1 肝星状细胞 分芽繁殖 胶原质 ET-1 分泌物 细胞内 钙浓度 HSCS
• 基金项目: Supported by the Grant for Nature and Science from Shanghai,No.03ZR 14097

AIM: To explore the effects of endothelin-1(ET-1) on hepatic stellate cells (HSCs) DNA uptake, DNA synthesis,collagen synthesis and secretion, inward whole-cell calcium concentration ([Ca^2+]i) as well as the blocking effect of verapamil on ET-l-stimulate