Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma／carcinoma cells

• 作 者: Zhi-HongZhang QinOuyang Hua-Ti
• 机 构: DepartmentofGastroenterology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2004年20期
• 关键词: 命中目标 环加氧酶-2 钠丁酸盐 NSAIDS 结直肠腺癌 癌细胞 肿瘤
• 基金项目: Supported by the Scientific Foundation of Sichuan Province,No.174

AIM: The protective effects of sodium butyrate and NSAIDs(especially the highly selective COX-2 inhibitors) have attracted considerable interest recently. In this study, primary adenoma cells and HT-29 were used to investigate whether the above drugs woul