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目的:评价中、加两国高剂量规格片剂分剂量是否节省成本。方法:通过统计文献资料中片剂的价格,计算价格波动度的大小及其分布、节省比例。结果:中、加两国临床常用的多种规格的片剂,其价格波动度(SP)均小于1。SP范围分别为0.13～0.83、0.00～0.99,节省比例范围分别为8.6%～43.7%、0.3%～50.0%。加拿大SP分布在0～0.33范围的比例更多,两国比较有显著性差异(P<0.05)。结论:与应用低剂量规格比较,中、加两国高剂量规格片剂分剂量服用时均能节省成本,但加拿大节省的成本更多。
OBJECTIVE: To evaluate whether cost-effective administration of high-dose tablets in both China and Canada is cost-effective. Methods: By counting the price of tablets in the literature, calculate the size and distribution of price volatility and save the ratio. Results: The price volatility (SP) of both Chinese and Canadian clinical tablets with multiple specifications were all less than 1. The range of SP ranged from 0.13 to 0.83 and from 0.00 to 0.99, respectively, with the saving ratio ranging from 8.6% to 43.7% and 0.3% to 50.0% respectively. The distribution of SP in Canada ranged from 0 to 0.33, with a significant difference between the two countries (P <0.05). Conclusion: Compared with the application of low-dose specifications, both Chinese and Canadian high-dose tablets can save cost when taken in divided doses, but the cost savings in Canada are more.