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205名1～5岁儿童,按血清维生素A含量和膳食中维生素A摄入水平分为2组。用单盲法每季度给实验组儿童补充50 000IU的维生素A,随访观察1年实验组和对照组儿童每人每年平均腹泻发病次数分别为0.089±0.02和0.347±0.30次;呼吸道感染性疾病分别为0.346±0.06和0.951±0.11次;每次病程天数分别为2.67±0.07与5.54±0.11和0.94±0.20与2.47±0.26天,均有统计学上的差异(P<0.05)。实验组儿童血清维生素A(1.22±0.06μmol/L)含量明显高于对照组(0.87±0.05μmol/L),也有非常显著性的差异(P<0.01)。结果说明该观察点儿童维生素A营养水平很低,补充维生素A后,可减少腹泻和呼吸道感染性疾病的发病率。
205 children aged 1 to 5 years were divided into two groups according to the level of serum vitamin A and dietary vitamin A intake. The single-blind method was used to supplement 50 000 IU of vitamin A to the experimental group children every quarter. The follow-up observation showed that the average incidence of diarrhea incidence per year was 0.089 ± 0.02 and 0.347 ± 0.30 in the experimental group and the control group respectively. Respiratory infectious diseases Were 0.346 ± 0.06 and 0.951 ± 0.11 times. The duration of each course was 2.67 ± 0.07 and 5.54 ± 0.11 and 0.94 ± 0.20 and 2.47 ± 0.26 days, respectively, with statistical difference (P <0.05). The level of serum vitamin A (1.22 ± 0.06μmol / L) in the experimental group was significantly higher than that in the control group (0.87 ± 0.05μmol / L), with significant difference (P <0.01). The results show that the observation point of vitamin A nutrition in children is very low, vitamin A, can reduce the incidence of diarrhea and respiratory tract infections.