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目的:通过体内雌、孕激素及血HCG检测,找到一种简单易行且行之有效的判断患者预后的方法。方法:随机选择100例胎动不安患者和50例正常妊娠者,在各组间不同时间段测定血清HCG、雌二醇以及孕酮值,绘制变化曲线,将胎动不安流产与保胎成功的患者之间拟合曲线相互比较,胎动不安流产与保胎成功的患者分别与正常妊娠相互比较,从而找到血清HCG、雌二醇以及孕酮值的变化对不同妊娠结局是否有预测作用。结果:不同妊娠时间,胎动不安患者发生流产的患者与得以继续妊娠的患者之间及正常妊娠患者之间,血清HCG及E2在变化趋势上存在明显差异。结论:妊娠7周时无论是HCG和E2在保胎成功和失败的患者间存在明显的分界点,提示我们在早期确认宫内妊娠后,在7~8周之间测激素水平预测胚胎发育正常与否是很必要的。
OBJECTIVE: To find a simple, effective and effective method for judging the prognosis of patients through the detection of estrogen, progesterone and blood HCG in the body. Methods: 100 cases of fetal distress and 50 cases of normal pregnancy were randomly selected. Serum HCG, estradiol and progesterone were measured at different time points among different groups, and the curves were drawn. The patients with fetal distress and spontaneous abortion The fitted curves were compared with each other. Fetal disturbed abortion and successful miscarriage were compared with normal pregnancy respectively to find out whether the change of serum HCG, estradiol and progesterone value had predictive effects on different pregnancy outcomes. Results: There was a significant difference in the change tendency of serum HCG and E2 between patients with different stages of pregnancy and fetal distress, patients with continuous pregnancy, and patients with normal pregnancy. CONCLUSIONS: At 7 weeks of gestation, there was a clear cut-off point between HCG and E2 in patients with failed or failed miscarriage, suggesting that we expect hormone levels to predict normal embryo development between 7 and 8 weeks after early confirmation of intrauterine pregnancy Whether or not it is necessary.