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目的探讨栓塞化疗联合放疗治疗原发性肝癌的临床疗效。方法按照随机数字表法将90例原发性肝癌患者随机分为观察组(45例)和对照组(45例),所有患者均给予护肝、对症支持等综合治疗。观察组及对照组患者均给予肝动脉栓塞化疗,观察组患者在栓塞化疗结束一个月后开始放射治疗。结果治疗后观察组患者肿瘤缓解情况及血清AFP治疗情况均显著优于对照组(P<0.05);两组患者不良反应情况差异无统计学意义(P>0.05)。结论栓塞治疗联合三维适形放疗治疗原发性肝癌具有较好的临床疗效,安全可行,值得临床借鉴。
Objective To investigate the clinical efficacy of embolization chemotherapy combined with radiotherapy in the treatment of primary liver cancer. Methods Ninety patients with primary liver cancer were randomly divided into observation group (n = 45) and control group (n = 45) according to random number table method. All patients were given comprehensive treatment of liver protection and symptomatic support. The patients in the observation group and the control group were given hepatic arterial chemoembolization and the patients in the observation group started radiotherapy one month after the end of embolization and chemotherapy. Results After treatment, the patients in the observation group had significantly better response to tumor and serum AFP treatment than those in the control group (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion Embolization combined with three-dimensional conformal radiotherapy for the treatment of primary liver cancer has good clinical efficacy, safe and feasible, is worthy of clinical reference.