大鼠黑质、被盖腹侧区胆囊收缩素样阳性神经元的分布及向尾壳核的投射双标记研究

• 作 者: 马奎元 胡海涛 任惠民 卢守祥
• 机 构: 济宁医学院人体解剖学教研室,西安医科大学人体解剖学教研室,西安医科大学人体解剖学教研室,西安医科大学人体解剖学教研室
• 出 处: 济宁医学院学报
• 发表日期: 1990年04期
• 关键词: 黑质 尾壳核 腹侧 胆囊收缩素 大鼠 HRP 网状部 肽能纤维 阳性神经元 免疫细胞化学

本文采用免疫细胞化学卵白素—生物素—过氧化物酶复合体法结合HRP 逆行追踪双标记技术,研究了中脑黑质和被盖腹侧区胆囊收缩素样阳性神元经分布及其向尾壳核的肽能纤维投射。结果显示:胆囊收缩素样阳性神经元分布于黑质致密部和外侧部以及被盖腹侧区,黑质网状部末见到胆收缩素样阳性神经元和纤维;黑质致密部和被盖腹侧区胆囊收缩素阳性神经元向同侧尾壳核发出纤维投射。

In this study, immunocytochemistry avidin-biotin-peroxidase complex combined with HRP retrograde tracing double-labeling technology to study the substantia nigra and the ventral area of ​​the gallbladder constrictor-like positive neurons by the distribution and direction Peptides of the caudate putamen project to the fiber. The results showed that the cholecystokinin-like neurons were distributed in the substantia nigra pars compacta and the lateral part, and the ventral part of the veil. The neurons and fibers of the cholecystokinin-like positive cells were seen in the nigral reticular part. The substantia nigra pars compacta Cholecystokinin-positive neurons in the ventral tegmental area issue fiber projections to the ipsilateral caudate putamen.