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目的研究乙肝后肝硬化患者消化性溃疡的临床特点,探讨小剂量心得安对肝源性溃疡愈合的影响。方法肝源性溃疡45例,观察其发病年龄、临床表现、溃疡部位、Hp感染率和并出血率及溃疡愈合率等特点。随机分为治疗组,用心得安 +泰胃美治疗;对照组,用维生素B6 +泰胃美治疗.另外选单纯性消化性溃疡22例,作为对照2组,治疗方法与对照组相同.结果肝源性溃疡发病年龄较单纯性消化性溃疡晚10年,溃疡部位以胃溃疡居多和并出血率高,.心得安可明显提高肝源性溃疡愈合率与对照组具统计学意义(P<0.05)。结论肝源性溃疡难以治愈且易并出血,门静脉高压因素可能从中发挥的作用,小剂量心得安有助于肝源性溃疡愈合
Objective To study the clinical characteristics of peptic ulcer in patients with posthepatitic cirrhosis and to explore the effect of low dose propranolol on the healing of liver ulcer. Methods Forty-five patients with liver-derived ulcer were observed for their age, clinical manifestations, ulcer sites, Hp infection rate, bleeding rate and ulcer healing rate. The patients in the control group were treated with Vitamin B6 + Tai Weimei, and other 22 cases of simple peptic ulcer were used as the control group 2. The treatment method was the same as the control group.Results The incidence of liver-derived ulcer than simple peptic ulcer 10 years later, the majority of gastric ulcer ulcer sites and the high rate of bleeding, the experience of Anker significantly improve the healing rate of liver ulcer with the control group with statistical significance (P < 0.05). Conclusions Hepatic ulcer is difficult to cure and easy to hemorrhage. The effect of portal hypertension may play a role, and low-dose prophylaxis helps to heal liver ulcer