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催乳素是腺垂体嗜酸粒细胞分泌的一种纯蛋白激素,由199个氨基酸残基所组成,分泌的调节与下丘脑有关。主要作用是发挥亲乳腺效应,刺激乳腺泌乳,并维持泌乳状态。研究显示,催乳素水平与人类一些自身免疫紊乱疾病的活跃性密切相关,这类疾病包括系统性红斑狼疮、类风湿关节炎、瑞特综合征等。现对催乳素在系统性红斑狼疮发病中的作用及与系统性红斑狼疮活跃性的关系进行综述。
Prolactin is a pure pheromone hormone secreted by the pituitary gland. It consists of 199 amino acid residues and its secretion is regulated by the hypothalamus. The main function is to play a pro-mammary gland effect, stimulate breast lactation, and maintain lactation status. Studies have shown that prolactin levels are closely related to the activity of some autoimmune disorders in humans, including systemic lupus erythematosus, rheumatoid arthritis and Reiter’s syndrome. Now on the role of prolactin in the pathogenesis of systemic lupus erythematosus and its relationship with the activity of systemic lupus erythematosus.