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临床上一直建议补充抗氧化性的维生素以降低先兆子痫和围产期并发症的风险,但是对这种干预疗法的疗效尚不确定。RumboldAR等人进行了一项多中心随机试验,研究对象为怀孕14～22周的初产妇。将其随机分配接受每天1000mg维生素C和400IU的维生素E或安慰剂(微晶纤维素)治疗,直至分娩
Clinically it has been proposed to supplement the antioxidant vitamins to reduce the risk of preeclampsia and perinatal complications, but the efficacy of this intervention is uncertain. RumboldAR et al. Conducted a multicenter randomized trial of primipara between 14 and 22 weeks of pregnancy. They were randomized to receive 1000 mg of vitamin C per day and 400 IU of vitamin E or placebo (microcrystalline cellulose) until delivery