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低出生体重儿向来易发生佝偻病。本文报告关于极小早产儿佝偻病的发生率及用活性型Vit D 的一种1α—OH—D_3治疗、预防佝偻病的成效。一、对象及方法:取1977.6～1979.6两年间出生体重<1500g 极小未熟儿27例。生后1～8个月中,每2周～1个月摄手关节X 光片1次。X 光片出现明显缺损及脱钙,血清硷性磷酸酶升高者诊断为佝偻病。同时测血清钙、磷,部分病例测血浆25—OH—D。佝偻病者投给1α—OH—D_3,0.1μg/kg/日;预防投药给0.1μg/kg/日4例,给0.05/μg/
Low birth weight children have always been prone to rickets. This article reports on the incidence of rickets in very small premature infants and the efficacy of a 1α-OH-D_3 treatment with active Vit D to prevent rickets. First, the object and methods: Take 1977.6 ~ 1979.6 two years born weighing <1500g 27 cases of infantile immature children. 1 to 8 months after birth, every 2 weeks ~ 1 month radiographs X-ray film 1 time. X-ray obvious defect and decalcification, elevated serum alkaline phosphatase were diagnosed as rickets. At the same time measure serum calcium, phosphorus, in some cases measured plasma 25-OH-D. Rickets patients were given 1α-OH-D_3,0.1μg / kg / day; prophylaxis administration to 0.1μg / kg / day in 4 cases, to 0.05 / μg /