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目的探讨肾综合征出血热(HFRS)引起肝脏损害的发生情况及预后。方法对24例HFRS患者根据病情进行分型并检测各期肝功能、肾功能情况。结果24例HFRS合并肝损害者16例,肝损害发生率66.67%。发热期、休克/少尿期、多尿期、恢复期ALT异常率分别为9/24(37.5%)、19/22(86.36%)、8/24(33.33%)、3/24(12.5%)。结论重型、危重型肝功能损害出现早、发生率高,休克/少尿期肝功能损害发生率高。ALT及TB IL升高与HFRS病情成正比,对HFRS病情预后及治疗有意义。
Objective To investigate the incidence and prognosis of liver damage caused by hemorrhagic fever with renal syndrome (HFRS). Methods Twenty-four patients with HFRS were classified according to their condition and the liver function and renal function were examined. Results Twenty-six patients with HFRS complicated with liver damage had a liver injury rate of 66.67%. The abnormal ALT rates of fever, shock / oliguria, polyuria and recovery were 9/24 (37.5%), 19/22 (86.36%), 8/24 (33.33%), 3/24 ). Conclusions The occurrence of severe and critically ill liver dysfunction is early and the incidence is high, and the incidence of hepatic dysfunction in shock / oliguria period is high. Elevated ALT and TB IL are directly proportional to the severity of HFRS, which is of significance for prognosis and treatment of HFRS.