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本文对24例HBsAg阳性母亲及其婴儿与21例HBsAg阴性母亲及其婴儿进行乙型肝炎病毒(HBV)母婴传播三年观察。结果表明观察组母亲HBsAg自然转阴9例(37.5％)其婴儿乙肝感染16例(66.7％);对照组母亲乙肝感染8例(38.l％),其婴儿乙肝感染9例(42.9％)。观察组婴儿乙肝感染率高于对照组婴儿,经统计学处理(P>0.05)差异无显著意义。同时,也对影响母婴传播的有关因素进行了初步探讨。此外,观察组16例受感染婴儿有7例(43.8％)发展为抗原血症,而这些对象表现为两个特点:1、大部份感染发生在6个月内,2、无临床症状呈现为亚临床型。
In this paper, 24 cases of HBsAg positive mothers and their infants and 21 cases of HBsAg negative mothers and their infants Hepatitis B virus (HBV) mother to child transmission for three years. The results showed that in the observation group, 9 cases (37.5%) of HBsAg naturally negative in the observation group had 16 cases (66.7%) of hepatitis B infection in their mothers, 8 cases (3.8%) had hepatitis B infection in the mother group, 9 cases (42.9% . The infection rate of hepatitis B in infants in observation group was higher than that of infants in control group, and there was no significant difference after statistical analysis (P> 0.05). At the same time, the factors influencing mother-to-child transmission were also discussed. In addition, seven (43.8%) of the 16 infected infants in the observation group developed antigenemia, and these subjects showed two characteristics: 1, most infections occurred within 6 months, 2, no clinical symptoms were present For subclinical.