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目的 :为了评价经内镜射频加局部化疗与单纯局部化疗的疗效。方法 :对 4 1例失去手术指征的晚期食管癌、胃癌进行射频加局部化疗或单纯局部化疗以评价二者疗效。该研究采用射频加局部化疗组 2 1例 ,局部注射化疗组 2 0例。治疗 1疗程后观察消化道梗阻缓解率。结果 :射频加局部化疗组 2 1例 ,治疗 1疗程后消化道梗阻缓解率 (显效 +有效 )为 95 .2 % (2 0 / 2 1) ,单纯局部化疗组为 5 5 % (11/ 2 0 ) ,两组相比有统计学差异 (P<0 .0 5 )。结论 :射频加局部化疗与单纯局部化疗两种方法均有效。射频加局部化疗优于单用局部注射化疗药物 ,提示对晚期食管癌、胃癌的治疗应尽量采用射频加局部化疗的方法
Objective: To evaluate the efficacy of endoscopic radiofrequency plus local chemotherapy and simple local chemotherapy. Methods: Forty-one patients with advanced esophageal cancer and gastric cancer who had lost operation indications were evaluated by radiofrequency plus local chemotherapy or simple local chemotherapy. In the study, 21 cases were treated with radiofrequency plus local chemotherapy and 20 cases with local injection chemotherapy. Treatment of a course of treatment to observe the response rate of digestive tract obstruction. Results: Twenty-one cases were treated with radiofrequency plus local chemotherapy. The response rate of digestive tract obstruction (effective and effective) was 95.2% (20/21) after treatment for one course of treatment and was 55% (11/2) 0), there was a significant difference between the two groups (P <0.05). Conclusion: Both radiofrequency plus local chemotherapy and simple local chemotherapy are effective. Radiotherapy plus local chemotherapy is better than single injection of chemotherapy drugs, suggesting that the treatment of advanced esophageal cancer, gastric cancer should try to use radio frequency plus local chemotherapy