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目的检测多菇口服液作为保健食品的安全性。方法通过小鼠经口急性毒性试验、致突变试验,大鼠30d喂养试验对多菇口服液进行检测。结果小鼠经口LD50>21.5g/kg,属无毒级物质;致突变试验结果为阴性;大鼠30d喂养试验表明各剂量组体重增长、食物利用率、脏体比、血液学及血清生化指标与对照组比较均无显着性差异(P>0.05)。病理检查主要脏器未发现与实验有关的病理性改变。结论多菇口服液为无毒、无致突变作用的保健食品。
Objective To detect the safety of Dokuo oral liquid as a health food. Methods Mice oral acute toxicity test, mutagenicity test, 30d rat feeding test for the detection of the mushroom. Results Mice oral LD50> 21.5g / kg, is a non-toxic substances; mutagenicity test results were negative; 30d rat feeding test showed that each dose group weight gain, food utilization, dirty body, hematology and serum biochemistry There was no significant difference between the index and the control group (P> 0.05). Pathological examination of the main organs found no experimental pathological changes. Conclusion Dokui oral solution is non-toxic, non-mutagenic health food.