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目的探讨儿童急性白血病(AL)患者医院感染的特点及相关危险因素。方法对2005年1月-2006年12月457例AL患者进行了临床调查分析。结果457例AL患者医院感染80例,医院感染率17.51%,感染例次率22.32%,感染部位以上呼吸道感染占首位,为42.16%;医院感染的发生与患者的年龄、住院时间、血红蛋白、中性粒细胞绝对值等有明显关系。结论积极治疗原发病,缩短平均住院日,提高中性粒细胞数及血红蛋白含量,严格规范使用抗菌药物,控制和预防医院感染发生。
Objective To investigate the characteristics of nosocomial infection in children with acute leukemia (AL) and related risk factors. Methods 457 cases of AL patients from January 2005 to December 2006 were investigated. Results 457 AL patients had nosocomial infection in 80 cases, the hospital infection rate was 17.51%, the infection rate was 22.32%, and the infection area above the respiratory tract infection was the highest (42.16%). The incidence of nosocomial infection was related to the patient’s age, length of hospital stay, hemoglobin The absolute value of granulocytes have a clear relationship. Conclusion Active treatment of primary disease, shorten the average length of stay, increase the number of neutrophils and hemoglobin content, strictly regulate the use of antimicrobial agents, control and prevention of nosocomial infections.