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早在20多年前,Child等已提示手术后的存活率可根据肝病的严重程度来预测,但常规肝功能检查很难对肝功能作出定量估计。当肝硬变进展时,周围动静脉分流可导致血流动力学亢进状态,诸如心脏指数(CI)增加、总周围阻力(TPR)下降、动静脉含氧量差别(AVD)减少。如肝功能损害是主要的生理紊乱,测定上述动力亢进状态的生理性心血管测定可预测病人的预后。靛氰绿廓清试验与功能性肝细胞团块呈正比,可用作预后的评估。
As early as more than 20 years ago, Child et al. Have shown that the survival rate after surgery can be predicted based on the severity of liver disease, but it is difficult to make a quantitative assessment of liver function by routine liver function tests. Circulation of arteriovenous shunts can lead to hyperkinetic states such as increased cardiac index (CI), decreased total peripheral resistance (TPR), and reduced arteriovenous oxygen differences (AVD) as cirrhosis progresses. If liver dysfunction is a major physiological disorder, physiological cardiovascular tests to determine the above state of hyperkinetic disease predict the prognosis of the patient. Indocyanine green clearance test is proportional to functional liver cell mass and can be used as a prognostic assessment.