论文部分内容阅读
目的对１９８９年启东肝癌筛检资料估计可检测的临床前期（ＤｅｔｅｃｔａｂｌｅＰｒｅ┐ｃｌｉｎｉｃａｌＰｈａｓｅ，ＤＰＰ）的值。方法用Ｗｅｉｓｓ提出的从模型最大对数似然函数值取极大值时，所对应的ＤＰＰ假定长度为ＤＰＰ的最佳估计。结果用ＡＦＰ和Ｂ超筛检原发性肝癌的ＤＰＰ为１２个月。结论在进行肝筛检效益的评价时，应考虑病例和对照在病例诊断前一年内进行的筛检
Objective To estimate the detectable preclinical phase (DPP) value of Qidong liver cancer screening data in 1989. When the maximum log-likelihood function value from the model is taken as the maximal value using the method proposed by Weiss, the corresponding DPP assumed length is the best estimate of DPP. Results The DPP of primary liver cancer was 12 months with AFP and B-ultrasound. Conclusion When evaluating the benefits of liver screening, screening of cases and controls within one year before case diagnosis should be considered