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目的 :比较两种方案治疗小儿急性重度以上特发性血小板减少性紫癜 (ITP)的疗效。方法 :于 1998年 10月～ 2 0 0 2年 10月分别采用甲基强的松龙冲击或甲基强的松龙冲击 +HDIVIG两种方案抢救 98例急性重度以上ITP患儿 ,比较两种方案治疗反应。结果 :甲基强的松龙冲击或甲基强的松龙冲击 +HDIVIG治疗急性重度以上ITP疗效肯定 ,甲基强的松龙冲击 +HDIVIG治疗提升血小板计数达安全范围 ( >3 0× 10 9/L)的平均时间、血小板计数达正常的平均时间、血小板计数达峰值的平均时间优于单用甲基强的松龙冲击治疗者 ,两组血小板峰值无显著性差异。结论 :甲基强的松龙冲击或甲基强的松龙冲击 +HDIVIG治疗急性重度以上ITP疗效肯定 ,甲基强的松龙冲击 +HDIVIG疗效优于单用甲基强的松龙冲击者
Objective: To compare the efficacy of the two regimens in the treatment of children with acute severe over idiopathic thrombocytopenic purpura (ITP). Methods: From October 1998 to October 2002, 98 patients with acute severe ITP were treated with methylprednisolone or methylprednisolone + HDIVIG respectively. Program treatment response. Results: Methylprednisolone or methylprednisolone + HDIVIG was effective in treating acute severe acute myocardial infarction (ITP). Methylprednisolone + HDIVIG increased the platelet count to a safe range (> 30 × 10 9) / L), mean platelet count up to normal, and mean platelet count up to peak were superior to those treated with methylprednisolone alone. There was no significant difference in peak platelet counts between the two groups. Conclusion: Methylprednisolone or methylprednisolone + HDIVIG is effective in the treatment of acute severe ITP. Methylprednisolone + HDIVIG is better than methylprednisolone