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曾有报告提示慢性肾功能衰竭患者中继发性甲状旁腺机能亢进与贫血之间有直接关系,行甲状旁腺切除术后可使贫血改善。然而,本文作者通过研究,提出不同的结论。96例慢性肾功能衰竭患者,男60例,女36例,年龄为15～73岁,接受血液透析3～113个月。依其免疫反应性甲状旁腺激素水平将患者分为3组:第1组为正常组27例,甲状旁腺激素<850pg/ml;第2组在43例,甲状旁腺激素<3,000pg/ml;第3组26例,甲状旁腺激素水平很高,只有在其血清稀释以后可测定。测定3组患者红细胞压积、钙、磷和碱性磷酸酶水平,并比较各组间的关系。此外,对18例行甲状旁腺切除术患者,在手术前和手术后12个月内测定平均红细胞压积,并进行比较.结果 3组患者的平均年龄和血液透析时限相似,血钙水平也相似。分别为9.2±0.2,8.98±0.1
There have been reports suggesting that there is a direct relationship between secondary hyperparathyroidism and anemia in patients with chronic renal failure and that anemia may be ameliorated after parathyroidectomy. However, the author of this paper puts forward different conclusions through research. 96 cases of chronic renal failure patients, 60 males and 36 females, aged 15 to 73 years, hemodialysis for 3 to 113 months. The patients were divided into 3 groups according to the level of their immunoreactive parathyroid hormone: group 1 was normal group (n = 27), parathyroid hormone (pg / ml) was lower than 850 pg / ml, group 2 was 43, parathyroid hormone was less than 3,000 pg / ml; Group 3, 26 cases, parathyroid hormone levels are high, only after its serum dilution can be measured. The hematocrit, calcium, phosphorus and alkaline phosphatase levels were measured in three groups and the relationship between groups was compared. In addition, 18 patients undergoing parathyroidectomy, preoperative and postoperative 12-month mean hematocrit were measured and compared.Results The average age of 3 patients was similar to the hemodialysis time, similar. Respectively, 9.2 ± 0.2,8.98 ± 0.1