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近年关于小儿难治性肾脏病治疗方法的进展是惊人的。甲基强的松龙短期大剂量治疗法(冲击疗法),试用于肾移植后急性排异反应的治疗。之后在欧美和日本,开始对急进性肾炎等难冶性肾脏病进行治疗引起了重视。这次我们在难治性肾脏病(以急进性肾炎为重点)有机会试用冲击疗法,特别在使用冲击疗法时,为了预防或者治疗大剂量类固醇产生的高凝状态并用纤溶疗法(尿激酶),进行有关临床及血凝、纤溶效果的探讨。对象及方法从临床经过及肾活组织的检查,对象是4例急进性肾炎(5～8岁男孩1例,女孩3例),临床所见
In recent years, progress on the treatment of pediatric refractory kidney disease is staggering. Methylprednisolone short-term high-dose therapy (impact therapy), for the treatment of acute rejection after renal transplantation. After that, in Europe, the United States and Japan began to pay attention to the treatment of refractory kidney disease such as acute nephritis. This time we have a chance to try out therapies for refractory kidney disease, which focuses on acute nephritis, especially when using shock therapy, in order to prevent or treat the hypercoagulable state of high-dose steroids and to use fibrinolytic therapy (urokinase) , For clinical and hemostatic, fibrinolytic effect of the discussion. Subjects and methods from clinical and renal biopsy examination, the object is 4 cases of acute nephritis (5 to 8 years old boy in 1 case, 3 girls), the clinical findings