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钙拮抗剂为一新型的平滑肌松弛剂,近年发现此类药物对神经疾病有治疗作用。本文对此作了简要分类,指出平滑肌收缩的共同途径和脑、脊髓、肌肉多种疾病细胞损伤的共同特征为细胞内Ca~(++)的增加。新的钙拮抗剂nimodipine、氟苯桂嗪等对脑血管的扩张作用,能改善脑微循环和保护脑细胞,适用于多种神经系统疾病的治疗。
Calcium antagonists for a new type of smooth muscle relaxants, in recent years found that such drugs have a therapeutic effect on neurological diseases. This article has made a brief classification, pointed out that the common pathway of smooth muscle contraction and brain, spinal cord, muscle cell damage in a common feature of intracellular Ca ~ (++) increase. The new calcium antagonist nimodipine, flubenzuron and other cerebrovascular expansion, can improve cerebral microcirculation and protect brain cells, suitable for a variety of neurological diseases.