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肿瘤浸润和转移在肿瘤的发展过程中起着至关重要的作用。肿瘤的浸润和转移是肿瘤细胞与宿主细胞之间相互作用的连续过程。近年来 ,介导肿瘤与细胞外基质降解的相关基因引起了人们的极大关注。基质金属蛋白酶 (MMPs)则是依赖Zn2 +降解细胞外基底膜基质的一类蛋白水解酶。目前 ,
Tumor invasion and metastasis play a crucial role in the development of the tumor. Tumor invasion and metastasis is a continuous process of the interaction between tumor cells and host cells. In recent years, the genes involved in the degradation of tumor and extracellular matrix aroused great concern. Matrix metalloproteinases (MMPs) are a class of proteolytic enzymes that rely on Zn2 + to degrade extracellular matrix. Currently ,