论文部分内容阅读
目的 :了解慢性化脓性中耳炎 (CSOM )患耳脓性分泌物的细菌分布及药物敏感性 ,以指导临床用药。方法 :采集 92例武汉地区CSOM患者手术中的中耳炎性分泌物 ,分别进行需氧菌、厌氧菌培养及药物敏感试验。结果 :需氧菌培养阳性者 75例 ,阳性率 81.5 % ,主要致病菌为绿脓杆菌、金黄色葡萄球菌和变形杆菌。 3种致病菌均对环丙沙星敏感 (敏感率为 89.0 %、88.2 %和 85 .0 % )。厌氧菌培养阳性者 10例 ,阳性率 10 .9%。结论 :绿脓杆菌、金黄色葡萄球菌和变形杆菌是武汉地区CSOM的主要致病菌 ,三者对环丙沙星类抗生素的敏感率均较高。厌氧菌在CSOM的发病中起着重要的作用。
Objective: To understand the bacterial distribution and drug sensitivity of purulent secretions from chronic suppurative otitis media (CSOM) to guide clinical use. Methods: Ninety-two cases of otitis media secretions were collected from patients with CSOM in Wuhan. Aerobic and anaerobic bacterial cultures and drug sensitivity tests were performed. Results: 75 cases of aerobic culture positive, the positive rate of 81.5%, the main pathogens are Pseudomonas aeruginosa, Staphylococcus aureus and Proteus. All three kinds of pathogenic bacteria were sensitive to ciprofloxacin (the sensitivity rates were 89.0%, 88.2% and 85.0%). Anaerobic culture positive in 10 cases, the positive rate of 10.9%. Conclusion: Pseudomonas aeruginosa, Staphylococcus aureus and Proteus are the major pathogenic bacteria of CSOM in Wuhan. All three are sensitive to ciprofloxacin antibiotics. Anaerobic bacteria play an important role in the pathogenesis of CSOM.