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目的:探讨依那普利及银杏叶软胶囊对早期糖尿病肾病(DN)的疗效。方法:2009年10月至2011年10月揭阳市惠来县人民医院应用依那普利联合银杏叶软胶囊治疗50例DN患者,治疗前及治疗后3个月后观察比较收缩压、血肌酐(SCr)、尿素氮(BUN)、24 h尿蛋白定量的变化情况。结果:治疗3个月后,患者血压、SCr、BUN、24 h尿蛋白定量较治疗前明显下降(P<0.05)。结论:依那普利联合银杏叶软胶囊能有效降低收缩压,减少尿蛋白的排泄,有效延缓DN的进展。
Objective: To investigate the efficacy of enalapril and ginkgo leaf capsule on early diabetic nephropathy (DN). Methods: From October 2009 to October 2011, 50 patients with DN were treated with enalapril combined with Ginkgo biloba soft capsule in Huilai County People’s Hospital of Jieyang City. Before treatment and 3 months after treatment, systolic blood pressure, serum creatinine (SCr), urea nitrogen (BUN), 24 h urine protein quantitative changes. Results: After 3 months of treatment, the blood pressure, SCr, BUN and 24 h urinary protein in patients were significantly lower than those before treatment (P <0.05). Conclusion: Enalaprol combined with Ginkgo biloba capsule can effectively reduce the systolic blood pressure, reduce urinary protein excretion and effectively delay the progression of DN.