Diagnostic accuracy of a rapid fecal test to confirm H pylori eradication after therapy: Prospective

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:shyandi123
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AIM: To investigate the clinical performances of rapidstool test (ImmunoCard STAT HpSA, Meridian DiagnosticInc.) in the evaluation of eradication therapy of H pyloriand to compare it with a well-known and validatedlaboratory stool test (Amplified IDEA Hp StAR, Dako).METHODS: Stool samples of 122 patients wereevaluated after eradication therapy of H pylori. H pyloristatus was assessed by 13C-urea breath test (UBT).Stool specimens were tested using either the rapidimmunoassay kit or the laboratory immunoassay kit.RESULTS: Forty-three patients were infected and 79non-infected. Sensitivity and specificity of ImmunoCardSTAT and Hp StAR were 58.14% and 76.4%, and97.47% and 98.73%, respectively (P > 0.05). Overallagreement between the two tests was 92.6% (113 of122 cases).CONCLUSION: ImmunoCard STAT seems to haverather low performances, and it cannot be regarded as areliable tool in the post-treatment setting. Also Hp StARcannot be recommended to confirm H pylori eradicationafter treatment. AIM: To investigate the clinical performances of rapidstool test (ImmunoCard STAT HpSA, Meridian Diagnostic Inc.) in the evaluation of eradiation therapy of H pyloriand to compare it with a well-known and validated laboratory stool test (Amplified IDEA Hp StAR, Dako) .METHODS : Stool samples of 122 patients wereevaluated after eradiation therapy of H pylori. H pyloristatus was assessed by 13 C-urea breath test (UBT). Stool specimens were tested using either the rapidimmunoassay kit or the laboratory immunoassay kit .RESULTS: Forty-three patients were Sensitivity and specificity of ImmunoCardSTAT and Hp StAR were 58.14% and 76.4%, and 97.47% and 98.73%, respectively (P> 0.05). Overallagreement between the two tests was 92.6% (113 of 122 cases). CONCLUSION: ImmunoCard STAT seems to haverather low performances, and it can not be regarded as areliable tool in the post-treatment setting. Also Hp StARcannot be recommended to confirm H pylori eradicationafter treatment.
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