LOH-profiling by SNP-mapping in a case of multifocal head and neck cancer

• 作 者: Jens Pfeiffer Wolfgang Maier G
• 机 构: DepartmentofOtorhinolaryngology
• 出 处: 世界临床肿瘤学杂志
• 发表日期: 2012年2期
• 关键词: GENOME-WIDE analysis Head and neck CANCER Loss of HETEROZYGOSITY MULTIFOCAL CANC

AIM:To introduce an approach for the detection of putative genetic host factors that predispose patients to develop head and neck squamous cell carcinomas(HNSCC).METHODS:HNSCC most often result from the accumulation of somatic gene alterations found in tu