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采用双能X射线吸收术对541名绝经前后妇女进行骨密度测定。结果示:腰椎于30~35岁、股骨近端25~29岁骨密度达到峰值;绝经前没有明显的骨丢失(P>0.05),50岁以后骨密度明显降低(P<0.01);绝经后早期为骨密度加速丢失阶段,随后趋于缓慢;年龄相同而绝经年限不同,骨密度差异显著(P<0.01),绝经年限相同而年龄不同,无显著性差异(P>0.05);多元回归分析表明,绝经年限对骨量丢失的作用强于年龄,认为绝经是女性骨量丢失主要原因。
Bone mineral density measurements were performed on 541 premenopausal and postmenopausal women using dual energy X-ray absorptiometry. The results showed that the lumbar vertebrae reached the peak at the age of 30-35 years old and the proximal femur 25-29 years old. There was no obvious bone loss before the menopause (P> 0.05), and the bone mineral density was significantly decreased after the age of 50 (P <0.01) ); Early stage of postmenopausal accelerated loss of bone mineral density stage, and then tend to slow; same age and menopause, bone mineral density was significantly different (P <0.01), the same menopause age but different age, no significant difference (P> 0.05). Multivariate regression analysis showed that the effect of menopause on bone loss was stronger than that of men and that menopause was the main cause of bone loss in women.