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Based on the electrocatalytic oxidation of levodopa at gold electrode and the reduction of permanganate at platinum electrode,a novel flow injection irreversible biamperometric method is developed for the determination of levodopa under the potential difference of 0 V imposed between two electrodes.In H_2SO_4 solution,the linear relationships between currents and the concentrations of levodopa are obtained in the range from 0.04 mg/L to 20 mg/L,with the detection limit of 0.012 mg/L.The proposed method is applied to the determination of levodopa in pharmaceutical preparations.
Based on the electrocatalytic oxidation of levodopa at gold electrode and the reduction of permanganate at platinum electrode, a novel flow injection irreversible biamperometric method is developed for the determination of levodopa under the potential difference of 0 V imposed between two electrodes. In H 2 SO 4 solution, the linear relationships between currents and the concentrations of levodopa are obtained in the range from 0.04 mg / L to 20 mg / L, with the detection limit of 0.012 mg / L. The proposed method is applied to the determination of levodopa in pharmaceutical preparations.