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目的 :探讨西宁地区老年人多器官功能衰竭 (MOF)的特点及治疗。方法 :分析 1998年元月至 2 0 0 2年 12月 4年间 30例老年人MOF的特点及治疗 ,与同期的 36例青中年MOF进行比较。结果 :与青中年相比 ,老年人MOF的病死率较高 (P <0 .0 5 ) ,导致MOF的病因 ,老年人主要是严重感染 ,占 70 % ,青中年人仅为 2 5 % ,两者相比差别有显著性 (P <0 .0 0 5 )。青中年MOF主要由严重创伤导致 ,占 4 7.2 % ,老年人仅为 10 % ,(P <0 .0 0 5 ) ;老年人发生脏器衰竭数目 :2个脏器 9例 (30 % )、3个脏器 9例 (30 % )、4个脏器 6例 (2 0 % )、5个以上脏器 6例 (2 0 % ) ,青年人分别为 16例 (4 4.4 % )、12例 (33.3% )、5例 (13.9% )、3例 (8.3% )。结论 :在西宁地区老年人MOF主要由严重感染导致 ,脏器衰竭数目多、病死率高 ,有效的抗感染、早期氧疗是治疗和预防MOF的关键
Objective: To explore the characteristics and treatment of multiple organ failure (MOF) in the elderly in Xining area. Methods: The characteristics and treatment of MOF in 30 elderly people from January 1998 to December 2004 were analyzed, compared with 36 cases of young middle-aged MOF in the same period. Results: Compared with young middle-aged, the morbidity of MOF in the elderly was higher (P <0.05), leading to the etiology of MOF. The elderly were mainly infected with severe infection, accounting for 70% %, There is significant difference between the two (P <0.05). Youth middle-aged MOF was mainly caused by severe trauma, accounting for 42.2% and only 10% of the elderly (P <0.05). The number of organ failure in the elderly was 9 (30%) in 2 organs , 9 cases (30%) of 3 organs, 6 cases (20%) of 4 organs, 6 cases (20%) of 5 or more organs and 16 cases (44.4%) of young people respectively. Cases (33.3%), 5 cases (13.9%), 3 cases (8.3%). Conclusion: The MOF in elderly people in Xining is mainly caused by severe infection. The number of organ failure, the high mortality rate, effective anti-infection and early oxygen therapy are the key to the treatment and prevention of MOF