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目的:对1,6-二磷酸果糖治疗轮状病毒(RV)肠炎伴心肌损害的疗效进行临床分析。方法:以97例确诊为RV肠炎伴心肌损害的患儿作为临床研究对象。随机分作两组,观察组50例,对照组47例。两组均实施常规性治疗,对照组增加能量合剂治疗,观察组增加1,6-二磷酸果糖静脉滴注治疗,观察比较两组治疗前后的磷酸肌酸激酶同工酶(CK-MB)变化与疗效。结果:治疗后,两组患儿的CK-MB检查结果均有显著改善,差异具有统计学意义(P<0.05);但观察组CK-MB下降的幅度显著大于对照组(P<0.05)。观察组治疗的总有效率为98.00%,明显高于对照组的80.85%,差异具有统计学意义(P<0.05)。两组患儿治疗期间均未见明显的不良反应发生。结论:常规治疗联合1,6二磷酸果糖治疗RV肠炎伴心肌损害,疗效理想。
Objective: To evaluate the efficacy of fructose-1,6-diphosphate in the treatment of rotavirus (RV) enteritis with myocardial damage. Methods: A total of 97 children diagnosed with RV enteritis and myocardial damage were selected as the clinical study subjects. Randomly divided into two groups, observation group 50 cases, control group 47 cases. Both groups were given routine treatment, the control group increased energy mixture therapy, observation group increased intravenous infusion of fructose-1,6-diphosphate treatment, observed before and after treatment of two groups of CK-MB changes And efficacy. Results: After treatment, the results of CK-MB in both groups were significantly improved, the difference was statistically significant (P <0.05); however, the decrease of CK-MB in observation group was significantly greater than that in control group (P <0.05). The total effective rate of observation group was 98.00%, which was significantly higher than 80.85% of control group, the difference was statistically significant (P <0.05). No significant adverse reactions occurred in both groups during treatment. CONCLUSION: Conventional treatment combined with fructose-1,6 diphosphate in the treatment of RV enteritis accompanied by myocardial damage is effective.