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河豚鱼的种类达百种以上,共味远非他鱼所能及。1909年东京大学田原博士首次从虎纹河豚的卵巢提取毒素,并命名为河豚毒素(Tetro-dotoxin,TT)。1964年于京都的国际天然有机化合物学会上平田等人正式确定 TT 的分子式为 C_(11)H_(17)O_8N_3,其致死量为0.48mg/60kg。1952年横尾提到 TT 的分子结构中存在一个内酯环,是产生毒性的原因,如开环则毒性消失。由 TT 引起的生理障碍,主要是食后1～2小时出现的初期中毒症状:如嘴唇、指头的知
Puffer fish species of more than 100 kinds of total flavor far from his fish can. In 1909, Dr. Tahara of Tokyo University extracted toxins from the ovaries of the tiger puffer fish for the first time and named Tetro-dotoxin (TT). In 1964 Kyoto International Natural Organic Compound Institute Ping Ping, who formally established TT formula C_ (11) H_ (17) O_8N_3, the lethal dose of 0.48mg / 60kg. The late 1952 mentions the existence of a lactone ring in the molecular structure of TT, which is the cause of toxicity, such as the disappearance of toxicity when opened. Physiological disorders caused by the TT, mainly post-1 to 2 hours after the onset of symptoms of early symptoms: such as the lips, fingers know