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血友病具有抗第Ⅷ因子抗体之患者,如有严重出血,处理极为困难。本文报告一例20岁的血友病患者,血浆中的抗第Ⅷ因子抗体含量达8单位/毫升,发生了硬膜下血肿,神经系症状进行性恶化而入院。后经开颅去除血肿,、出院时仅有轻微的神经系缺陷。其治疗成功系由于两次应用持续流动的细胞分离器换血,应用环磷酞胺和皮质激素进行免疫抑制,并用了六胺基己酸和大剂量的抗血
Hemophilia Patients with anti-factor Ⅷ antibodies are extremely difficult to handle if they have severe bleeding. This article reports a 20-year-old hemophiliac in patients with plasma anti-factor Ⅷ antibody content of 8 units / ml, the occurrence of subdural hematoma, progressive deterioration of neurological symptoms and admission. After removing the hematoma by craniotomy, discharge only mild neurological defects. The success of its treatment due to two applications of continuous flow cell separator transfusion, the use of cyclophosphamide and corticosteroid immunosuppression, and hexamine hexanoate and high doses of anti-blood