Genomic integrity of human induced pluripotent stem cells:Reprogramming,differentiation and applicat

• 作 者: Clara Steichen Zara Hannoun El
• 机 构: INSERMU1082IRTOMIT,Université,dePoitiers,INSERMU1193,UMR_S1193,TheJennerInstitute,DepartementHos
• 出 处: 世界干细胞杂志:英文版(电子版)
• 发表日期: 2019年10期
• 关键词: Induced PLURIPOTENT stem cells GENOMIC integrity MUTATIONS KARYOTYPE DIFFERENTIA

Ten years after the initial generation of induced pluripotent stem cells(hiPSCs)from human tissues,their potential is no longer questioned,with over 15000 publications listed on PubMed,covering various fields of research;including disease modeling,cell th