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近年研究表明非甾体类抗炎药物对某些肿瘤具有抑制作用。本文采用噻唑蓝体外细胞毒试验（MTT），观察阿斯匹林对人胃癌细胞株SGC－7901的生长抑制作用。结果表明：阿斯匹林对SGC－7901生长有明显的抑制作用，其抑制率与阿斯匹林浓度和作用时间呈正相关性（r分别为0．8873和0．8256，P值均小于0．001）。小剂量阿斯匹林联合5－Fu作用于SGC－7901，其生长抑制率有明显提高。结论：阿斯匹林具有抑制人胃癌细胞株SGC－7901生长的作用，与5－Fu联用效果更佳。
Recent studies have shown that non-steroidal anti-inflammatory drugs have inhibitory effects on certain tumors. In this paper, thiazolyl blue in vitro cytotoxicity test (MTT) observed aspirin on human gastric cancer cell line SGC-7901 growth inhibition. The results showed that aspirin had a significant inhibitory effect on the growth of SGC-7901, and the inhibition rate was positively correlated with aspirin concentration and time (r = 0.8873 and 0.8256, respectively, P values were less than 0 .001). Small doses of aspirin combined with 5-Fu on SGC-7901, the growth inhibition rate was significantly improved. CONCLUSION: Aspirin can inhibit the growth of human gastric cancer cell line SGC-7901 and work well with 5-Fu.