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目的:探讨糖尿病患者应用中西医结合治疗临床疗效及其不良反应观察,为临床诊断治疗提供一定的参考价值。方法:本组82例糖尿病患者根据随机数字表法随机分为对照组和观察组各41例。对照组采用西药给予治疗,观察组在对照组基础上结合中药汤剂治疗。结果:观察组治疗后总有效率(92.68%)显著高于对照组(73.17%),且有统计学差异(P<0.05);观察组治疗后TC、TG、LDL变化显著低于治疗前及对照组治疗后,而HDL显著高于治疗前及对照组治疗后,且均有统计学差异(P<0.05);观察组治疗后FBG、2h PG及Hb A1c比较显著低于对照组治疗后,且有统计学差异(P<0.05);观察组治疗后血浆比黏度、纤维蛋白原及红细胞压积显著低于治疗前及对照组治疗后,且有统计学差异(P<0.05);观察组不良反应发生率显著低于对照组,且有统计学差异(P<0.05)。结论:糖尿病患者应用中西医结合治疗临床疗效显著,具有重要临床研究价值,值得进一步推广应用。
Objective: To investigate the clinical efficacy and adverse reactions of diabetic patients treated with integrated traditional Chinese and western medicine, and to provide some reference value for clinical diagnosis and treatment. Methods: 82 cases of diabetic patients were randomly divided into control group and observation group according to random number table method in 41 cases. The control group was treated with Western medicine, and the observation group was treated with Chinese medicine decoction on the basis of the control group. Results: The total effective rate (92.68%) in the observation group was significantly higher than that in the control group (73.17%) (P <0.05). The changes of TC, TG and LDL in observation group were significantly lower than those before treatment and before treatment After treatment, the HDL in the control group was significantly higher than that before treatment and in the control group (P <0.05). After treatment, the FBG, 2h PG and Hb A1c in the observation group were significantly lower than those in the control group (P <0.05). The plasma specific viscosity, fibrinogen and hematocrit in observation group were significantly lower than those before treatment and control group after treatment (P <0.05), and the observation group The incidence of adverse reactions was significantly lower than that of the control group (P <0.05). Conclusion: The clinical efficacy of diabetes mellitus patients treated with integrated traditional Chinese and western medicine is significant and has important clinical research value, which deserves further popularization and application.