论文部分内容阅读
伤口感染可用全身性抗生素防治，但抗生素的广泛应用易导致其耐药性的发生；伤口局部应用抗生素使其作用仅发生在伤口易感的靶组织中，Ostro等早在1987年就提出用微脂粒（Liposome）包裹抗生素能延长其释放时间而使局部作用持久。微脂粒是由脂膜小球组成，可包裹多种制剂，在宿主体内能生物降解，
Wound infection can be treated with systemic antibiotics, but the widespread use of antibiotics easily lead to the occurrence of drug resistance; local application of antibiotics wound so that its role only in the target tissue susceptible to wounds, Ostro et al as early as 1987 proposed a micro Liposomes encapsulate antibiotics to prolong their release time and prolong the local action. Liposomes are composed of lipid globules that can be wrapped in a variety of formulations that are biodegradable in the host body,