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［目的］对胃粘膜相关淋巴组织（ＭＡＬＴ）淋巴瘤浸润子宫平滑肌瘤临床病理、ＤＮＡ倍体进行研究。［方法］标本采用常规石蜡切片、ＨＥ染色及ＡＢＣ法免疫组化染色，并对Ｆｅｕｇｅｌｎ染色切片用细胞影像仪对瘤细胞的ＤＮＡ倍体进行测定。［结果］胃粘膜、粘膜下层、肌层及平滑肌瘤内均可见弥漫多量密集成片的中心细胞样瘤细胞浸润。胃、胃大弯淋巴结淋巴瘤细胞ＤＮＡ质量分布呈单个主峰，瘤细胞ＤＮＡ呈非整倍体。子宫肌瘤细胞ＤＮＡ的质量分布为两个峰，主峰为二倍体，次峰为非整倍体。本例预后不良。［结论］ＭＡＬＴ淋巴瘤浸润子宫肌瘤须与子宫原发性恶性淋巴瘤、慢性淋巴细胞性白血病浸润子宫及子宫内膜间质肉瘤相鉴别。随访结果表明ＤＮＡ指数对于患者预后的判断是一项重要的参考指标。
[Objective] To study the clinical pathological and DNA ploidy of uterine leiomyoma infiltrated by gastric mucosa-associated lymphoid tissue (MALT) lymphoma. [Methods] Specimens were routinely paraffin sectioned, stained with HE and immunohistochemically stained with ABC, and the DNA ploidy of tumor cells was measured with a cell imaging instrument for Feugeln staining. [Results] The central cell-like tumor cells infiltrated in a large number of densely-integrated patches in gastric mucosa, submucosa, muscularis and leiomyoma. The distribution of DNA mass in gastric lymph node lymphoma cells showed a single main peak, and the DNA of tumor cells was aneuploid. The mass distribution of DNA in uterine leiomyoma cells is two peaks, the main peak is diploid and the secondary peak is aneuploid. This case has a poor prognosis. [Conclusion] MALT lymphoma infiltrating uterine fibroids must be differentiated from primary uterine malignant lymphoma, chronic lymphocytic leukemia infiltrating uterus and endometrial stromal sarcoma. Follow-up results show that the DNA index is an important reference indicator for the prognosis of patients.