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用小剂量CCl_4制成小鼠肝微循环障碍LMCO(高度纤维化)模型。至270天,给CCl_450次即可制成各期LMCO(包括肝硬化及癌变)模型。三七可对抗CCl_4所致小鼠LMCO;可对抗DGalN所致大鼠肝血流量减少和家兔的急性肝损伤,能使中央静脉下成纤维细胞
A small dose of CCl_4 was used to generate LMCO (high degree of fibrosis) model of mouse liver microcirculation disorder. To 270 days, to CCl_450 times can be made of various stages LMCO (including cirrhosis and cancer) model. Notoginseng can fight against mice induced by CCl_4 LMCO; can be against DGalN-induced hepatic blood flow in rats and acute liver injury, can make central venous fibroblasts